Researchers have uncovered a rare inherited genetic mutation that can elevate an individual’s likelihood of developing lung cancer by approximately 25 times overall and by about 60 times among non-smokers, according to a pivotal study published in the journal Science. The investigation, carried out by scientists at the Dana-Farber Cancer Institute in collaboration with the 23andMe Research Institute, analyzed anonymized genetic information from over 3.3 million people. Lead researcher Dr. Jaclyn LoPiccolo remarked that carrying this variant increases lung cancer risk approximately 62 times among never-smokers, versus roughly 11 times in those with a history of smoking. Gene Variants Might Elevate Lung Cancer Risk by as Much as 60 Times in Non-Smokers.